Estradiol enantate/algestone acetophenide

Estradiol enanthate

Estradiol enantate/algestone acetophenide

Estradiol enantate/algestone acetophenide (also known as E2-EN/DHPA) is a combination medication used in hormonal contraception. It contains two active ingredients: estradiol enantate (E2-EN), an estrogen, and algestone acetophenide (DHPA), a progestin. This combination is used primarily as a combined injectable contraceptive.

Components

• Estradiol enantate (E2-EN): A synthetic ester of estradiol, a naturally occurring estrogen.
• Algestone acetophenide (DHPA): A synthetic progestin used in hormonal contraception.

Mechanism of Action

The combination of estradiol enantate and algestone acetophenide works by inhibiting ovulation, altering the endometrium to prevent implantation, and thickening the cervical mucus to inhibit sperm penetration.

Administration

Estradiol enantate/algestone acetophenide is administered via intramuscular injection. The typical regimen involves an injection every 30 days.

Side Effects

Common side effects may include:

• Nausea
• Headache
• Breast tenderness
• Weight gain
• Mood changes

Contraindications

This medication should not be used in individuals with:

• Thromboembolic disorders
• Liver disease
• Breast cancer
• Pregnancy

Related Pages

• Hormonal contraception
• Combined injectable contraceptive
• Estradiol enantate
• Progestin
• Estrogen

See Also

• Contraceptive methods
• Reproductive health