Acetylglycinamide

Acetylglycinamide is an organic compound with the formula C4H8N2O2. It is a derivative of glycinamide, which is a non-proteinogenic amino acid. Acetylglycinamide is used in the synthesis of various pharmaceuticals.

Structure and properties[edit | edit source]

Acetylglycinamide is a white crystalline solid. It is soluble in water and has a melting point of 187-189 °C. The compound has a molecular weight of 116.12 g/mol. It is a derivative of glycinamide, which is a non-proteinogenic amino acid. The compound is acetylated on the nitrogen atom of the amide group.

Synthesis[edit | edit source]

Acetylglycinamide can be synthesized from glycinamide by acetylation with acetic anhydride. The reaction is typically carried out in a solvent such as dichloromethane or ethyl acetate.

Applications[edit | edit source]

Acetylglycinamide is used in the synthesis of various pharmaceuticals. It is a key intermediate in the synthesis of acetohydroxamic acid, a drug used to treat urinary tract infections. It is also used in the synthesis of glycinex, a drug used to treat epilepsy.

Safety[edit | edit source]

As with all chemicals, acetylglycinamide should be handled with care. It may cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled.

See also[edit | edit source]

Acetylglycinamide Resources
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