Acetylmethadol

Acetylmethadol is a synthetic opioid similar in structure to methadone. It is a long-acting opioid that was previously used in the treatment of various conditions but is now largely discontinued due to its potential for misuse and addiction.

Overview

Acetylmethadol was developed in the 1940s as a potential treatment for opioid addiction. It is a derivative of methadone, a synthetic opioid that is still widely used today. Acetylmethadol has a longer duration of action than methadone, making it potentially useful in the treatment of opioid addiction. However, it also has a higher potential for misuse and addiction, which has led to its discontinuation in many countries.

Pharmacology

Acetylmethadol is a mu-opioid receptor agonist. It works by binding to the mu-opioid receptors in the brain, which are involved in the perception of pain. By binding to these receptors, acetylmethadol can reduce the perception of pain and produce a feeling of euphoria. However, this can also lead to the development of tolerance and dependence, which can result in addiction if the drug is misused.

Side Effects

The side effects of acetylmethadol are similar to those of other opioids. They can include drowsiness, nausea, constipation, and respiratory depression. In severe cases, misuse of acetylmethadol can lead to overdose and death.

History

Acetylmethadol was first synthesized in the 1940s as a potential treatment for opioid addiction. However, it was later found to have a high potential for misuse and addiction, and its use has been largely discontinued.

See Also

• Methadone
• Opioid addiction
• Opioid overdose

Acetylmethadol Resources
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