Acipimox
Acipimox is a niacin derivative used as a lipid-lowering agent. It works by inhibiting the body's production of fatty acids and reducing levels of triglycerides and low-density lipoprotein (LDL) cholesterol, while increasing levels of high-density lipoprotein (HDL) cholesterol.
Pharmacology[edit | edit source]
Acipimox is a niacin derivative that has lipid-lowering properties. It inhibits the release of fatty acids from adipose tissue, leading to a decrease in triglycerides and low-density lipoprotein (LDL) cholesterol, and an increase in high-density lipoprotein (HDL) cholesterol.
Clinical Use[edit | edit source]
Acipimox is used in the treatment of hyperlipidemia and dyslipidemia. It is particularly effective in reducing levels of triglycerides and low-density lipoprotein (LDL) cholesterol, and increasing levels of high-density lipoprotein (HDL) cholesterol.
Side Effects[edit | edit source]
Common side effects of Acipimox include flushing, itching, nausea, abdominal pain, and headache. In rare cases, it can cause hypotension, dizziness, and rash.
Contraindications[edit | edit source]
Acipimox is contraindicated in patients with liver disease, peptic ulcer disease, and gout. It should be used with caution in patients with diabetes due to the potential for hyperglycemia.
Interactions[edit | edit source]
Acipimox may interact with other lipid-lowering agents, antihypertensives, and anticoagulants. It may also interact with alcohol, which can increase the risk of flushing and itching.
See Also[edit | edit source]
Acipimox Resources | ||
---|---|---|
|
|
|
Find a healthcare provider anywhere in the world quickly and easily!
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
WikiMD is the world's largest, free medical and wellness encyclopedia edited only by professionals. Advertise!
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD