Acipimox

From WikiMD's Wellnesspedia

Acipimox is a niacin derivative used as a lipid-lowering agent. It works by inhibiting the body's production of fatty acids and reducing levels of triglycerides and low-density lipoprotein (LDL) cholesterol, while increasing levels of high-density lipoprotein (HDL) cholesterol.

Pharmacology[edit | edit source]

Acipimox is a niacin derivative that has lipid-lowering properties. It inhibits the release of fatty acids from adipose tissue, leading to a decrease in triglycerides and low-density lipoprotein (LDL) cholesterol, and an increase in high-density lipoprotein (HDL) cholesterol.

Clinical Use[edit | edit source]

Acipimox is used in the treatment of hyperlipidemia and dyslipidemia. It is particularly effective in reducing levels of triglycerides and low-density lipoprotein (LDL) cholesterol, and increasing levels of high-density lipoprotein (HDL) cholesterol.

Side Effects[edit | edit source]

Common side effects of Acipimox include flushing, itching, nausea, abdominal pain, and headache. In rare cases, it can cause hypotension, dizziness, and rash.

Contraindications[edit | edit source]

Acipimox is contraindicated in patients with liver disease, peptic ulcer disease, and gout. It should be used with caution in patients with diabetes due to the potential for hyperglycemia.

Interactions[edit | edit source]

Acipimox may interact with other lipid-lowering agents, antihypertensives, and anticoagulants. It may also interact with alcohol, which can increase the risk of flushing and itching.

See Also[edit | edit source]


Acipimox Resources

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Contributors: Prab R. Tumpati, MD