Acropustulosis

Acropustulosis is a rare, chronic skin condition that primarily affects infants and young children. It is characterized by the recurrent development of itchy, sterile pustules on the palms of the hands and soles of the feet.

Etiology

The exact cause of acropustulosis is unknown. However, it is believed to be an immune response to an unidentified antigen. Some researchers suggest that the condition may be triggered by an infection, insect bite, or exposure to certain medications or chemicals.

Symptoms

The primary symptom of acropustulosis is the appearance of small, itchy pustules on the palms and soles. These pustules often burst and crust over, leading to scaling and peeling of the skin. Other symptoms may include fever, malaise, and lymphadenopathy.

Diagnosis

Diagnosis of acropustulosis is primarily based on the clinical presentation. A skin biopsy may be performed to rule out other conditions that can cause similar symptoms, such as psoriasis, dermatitis, and scabies.

Treatment

Treatment of acropustulosis is aimed at relieving the symptoms and preventing flare-ups. Topical corticosteroids are commonly used to reduce inflammation and itching. In severe cases, systemic medications such as methotrexate or cyclosporine may be prescribed.

Prognosis

The prognosis for individuals with acropustulosis is generally good. The condition often resolves spontaneously by adolescence, although it can persist into adulthood in some cases.

See also

• Pustular psoriasis
• Dyshidrosis
• Palmoplantar pustulosis