Acute severe asthma

From WikiMD's Wellness Encyclopedia

Acute Severe Asthma, also known as status asthmaticus, is a critical condition that represents a severe, life-threatening exacerbation of asthma that is unresponsive to standard treatments. This condition requires immediate medical attention, as it can lead to respiratory failure and other serious complications without prompt and effective intervention.

Definition[edit | edit source]

Acute severe asthma is characterized by an intense and rapid worsening of asthma symptoms, including shortness of breath, wheezing, coughing, and chest tightness. Unlike regular asthma attacks, acute severe asthma does not respond well to standard reliever medications, such as short-acting beta agonists (SABAs), making it a medical emergency.

Causes[edit | edit source]

The exact cause of acute severe asthma can vary from person to person but is often triggered by factors such as:

  • Allergens (e.g., pollen, mold, pet dander, dust mites)
  • Respiratory infections
  • Air pollutants (e.g., tobacco smoke, chemical fumes)
  • Exercise
  • Stress
  • Nonadherence to asthma control medications

Symptoms[edit | edit source]

Symptoms of acute severe asthma include:

  • Extreme difficulty breathing
  • Inability to speak in full sentences
  • Severe wheezing and coughing
  • Rapid breathing
  • Cyanosis (bluish coloration of the lips or face due to lack of oxygen)
  • Use of accessory muscles to breathe
  • Altered level of consciousness

Diagnosis[edit | edit source]

Diagnosis of acute severe asthma involves a thorough medical history, physical examination, and tests such as:

  • Pulmonary function tests (PFTs), including spirometry, to assess the severity of airflow obstruction
  • Arterial blood gas (ABG) analysis to evaluate oxygen and carbon dioxide levels in the blood
  • Chest X-ray to rule out other causes of respiratory distress
  • Peak expiratory flow rate (PEFR) to measure the maximum speed of expiration

Treatment[edit | edit source]

Treatment for acute severe asthma aims to rapidly reverse airway obstruction and reduce inflammation. It typically involves:

  • High doses of inhaled corticosteroids
  • Systemic corticosteroids to reduce airway inflammation
  • Supplemental oxygen to maintain adequate oxygenation
  • Nebulized SABAs to relieve airway constriction
  • Possible admission to an intensive care unit (ICU) for those with life-threatening symptoms
  • In severe cases, mechanical ventilation may be required to support breathing

Prevention[edit | edit source]

Prevention of acute severe asthma involves:

  • Regular use of controller medications to maintain long-term asthma control
  • Avoidance of known triggers
  • Regular monitoring of asthma symptoms and lung function
  • Development of an asthma action plan in consultation with a healthcare provider

Complications[edit | edit source]

Complications of acute severe asthma can include:

  • Respiratory failure
  • Pneumothorax (collapsed lung)
  • Acute respiratory distress syndrome (ARDS)
  • Status asthmaticus can be fatal if not treated promptly and effectively

Conclusion[edit | edit source]

Acute severe asthma is a serious condition that requires immediate medical attention. With prompt and appropriate treatment, most individuals can recover from an acute severe asthma episode. However, it is crucial to manage asthma properly and avoid known triggers to prevent such severe exacerbations.


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Contributors: Prab R. Tumpati, MD