Acute yellow atrophy

Acute Yellow Atrophy

Acute yellow atrophy (AYA), also known as acute hepatic necrosis, is a rare and often fatal condition characterized by the rapid degeneration and necrosis of liver cells. This condition is typically associated with severe liver damage and is often seen in individuals with a history of excessive alcohol consumption or drug abuse.

Etiology

The exact cause of acute yellow atrophy is unknown, but it is often associated with severe liver damage due to alcohol abuse, drug abuse, or viral hepatitis. Other potential causes include autoimmune diseases, metabolic disorders, and toxic exposure.

Symptoms

Symptoms of acute yellow atrophy can vary widely, but often include jaundice (yellowing of the skin and eyes), abdominal pain, nausea, vomiting, and weight loss. In severe cases, patients may develop hepatic encephalopathy, a condition characterized by confusion, altered level of consciousness, and other neurological symptoms due to liver failure.

Diagnosis

Diagnosis of acute yellow atrophy is typically based on clinical symptoms, medical history, and laboratory tests. Imaging studies such as ultrasound, CT scan, or MRI may also be used to assess the extent of liver damage.

Treatment

Treatment for acute yellow atrophy is primarily supportive and aims to manage symptoms and prevent complications. This may include intravenous fluids, medications to manage symptoms, and in severe cases, liver transplantation.

Prognosis

The prognosis for acute yellow atrophy is generally poor, with a high mortality rate. However, early detection and treatment can improve survival rates.

See also

• Liver disease
• Hepatic encephalopathy
• Alcoholic liver disease
• Drug-induced liver injury