Adavosertib
Adavosertib (development codes AZD1775, MK-1775) is an experimental anti-cancer drug candidate. It is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity.[1] It is being developed by AstraZeneca.[2]
It is being investigated as a treatment for pancreatic cancer with phase 1 trial.[3][4] University of Michigan researchers are as of 2019 planning a phase 2 study.[5]
References[edit | edit source]
- ↑ "NCI Drug Dictionary". National Cancer Institute. 2 February 2011. Retrieved 17 August 2019.
- ↑ "AZD1775 | AstraZeneca Open Innovation". openinnovation.astrazeneca.com. Retrieved 17 August 2019.
- ↑ "Early Activity in Pancreatic [[Cancer]] With New Drug". www.medpagetoday.com. 16 August 2019. Retrieved 17 August 2019.
{{cite web}}: URL–wikilink conflict (help) - ↑
- ↑ "AstraZeneca drug heads to phase 2 in pancreatic cancer after small trial extends survival". FierceBiotech. Retrieved 17 August 2019.
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