Advanced sleep phase syndrome

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Advanced Sleep Phase Syndrome (ASPS) is a sleep disorder characterized by a significant shift in the timing of the major sleep period, either falling asleep or waking up several hours earlier than what is considered a normal sleep pattern. This syndrome is a type of circadian rhythm sleep disorder, which involves disruptions to the body's internal biological clock.

Symptoms[edit | edit source]

The primary symptom of Advanced Sleep Phase Syndrome is an extreme tendency to fall asleep early in the evening, often between 6 p.m. and 9 p.m., and wake up early in the morning, typically between 2 a.m. and 5 a.m. Other symptoms may include difficulty staying awake in the evening, waking up too early and not being able to go back to sleep, and experiencing excessive sleepiness in the early evening.

Causes[edit | edit source]

The exact cause of Advanced Sleep Phase Syndrome is not fully understood. However, it is believed to be influenced by a combination of genetic and environmental factors. Some studies suggest that mutations in certain genes, such as PER2 and CRY1, may be associated with the disorder. These genes play a crucial role in regulating the body's circadian rhythms.

Diagnosis[edit | edit source]

Diagnosis of Advanced Sleep Phase Syndrome typically involves a thorough medical history and a detailed sleep history. A sleep diary or actigraphy, a non-invasive method of monitoring human rest/activity cycles, may be used to track sleep patterns. In some cases, a polysomnography may be performed to rule out other sleep disorders.

Treatment[edit | edit source]

Treatment for Advanced Sleep Phase Syndrome typically involves chronotherapy, a behavioral technique that gradually delays the bedtime and wake time, and light therapy, which involves exposure to bright light upon waking to help reset the circadian rhythm. In some cases, medication may be used to help regulate sleep-wake cycles.

See also[edit | edit source]

Template:Circadian rhythm

Advanced sleep phase syndrome Resources
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Contributors: Prab R. Tumpati, MD