Alimentary toxic aleukia

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Alimentary toxic aleukia
File:Alimentary Toxic Aleukia.png
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Nausea, vomiting, diarrhea, leukopenia, hemorrhage, necrosis
Complications Bone marrow suppression, immunosuppression, sepsis
Onset Hours to days after ingestion
Duration Variable, can be chronic
Types N/A
Causes Ingestion of mycotoxins from Fusarium species
Risks Consumption of contaminated grain
Diagnosis Clinical evaluation, history of exposure, laboratory tests
Differential diagnosis Aplastic anemia, radiation sickness, other mycotoxicoses
Prevention Proper storage of grains, avoiding contaminated food
Treatment Supportive care, blood transfusion, antibiotics for secondary infections
Medication N/A
Prognosis Variable, can be fatal if untreated
Frequency Rare, associated with specific outbreaks
Deaths N/A


Alimentary toxic aleukia, is a mycotoxin-induced condition characterized by nausea, vomiting, diarrhea, leukopenia (aleukia), hemorrhaging, skin inflammation, and sometimes death. Alimentary toxic aleukia almost always refers to the human condition associated with presence of T2 Toxin.

History[edit]

Alimentary toxic aleukia was first characterized in the early 19th century after affecting a large population in the Orenburg district of the former U.S.S.R. during World War II. The sick people had eaten overwintered grain colonized with Fusarium sporotrichioides and Fusarium poae.