Alimentary toxic aleukia

Alimentary toxic aleukia
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Nausea, vomiting, diarrhea, leukopenia, hemorrhage, necrosis
Complications	Bone marrow suppression, immunosuppression, sepsis
Onset	Hours to days after ingestion
Duration	Variable, can be chronic
Types	N/A
Causes	Ingestion of mycotoxins from Fusarium species
Risks	Consumption of contaminated grain
Diagnosis	Clinical evaluation, history of exposure, laboratory tests
Differential diagnosis	Aplastic anemia, radiation sickness, other mycotoxicoses
Prevention	Proper storage of grains, avoiding contaminated food
Treatment	Supportive care, blood transfusion, antibiotics for secondary infections
Medication	N/A
Prognosis	Variable, can be fatal if untreated
Frequency	Rare, associated with specific outbreaks
Deaths	N/A

Alimentary toxic aleukia, is a mycotoxin-induced condition characterized by nausea, vomiting, diarrhea, leukopenia (aleukia), hemorrhaging, skin inflammation, and sometimes death. Alimentary toxic aleukia almost always refers to the human condition associated with presence of T2 Toxin.

History

Alimentary toxic aleukia was first characterized in the early 19th century after affecting a large population in the Orenburg district of the former U.S.S.R. during World War II. The sick people had eaten overwintered grain colonized with Fusarium sporotrichioides and Fusarium poae.