Allyltrimethylsilane

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Allyltrimethylsilane is a chemical compound used in organic synthesis. It is a colorless liquid that is stable under normal conditions. The compound is used as a reagent in the synthesis of various organic compounds.

Chemical Properties[edit | edit source]

Allyltrimethylsilane has the chemical formula C6H14Si. It is a member of the silane family of compounds, which are characterized by a silicon atom bonded to four other atoms. In the case of allyltrimethylsilane, the silicon atom is bonded to three methyl groups and one allyl group.

The allyl group in allyltrimethylsilane is a reactive group that can participate in various chemical reactions. This makes the compound a useful reagent in organic synthesis.

Uses in Organic Synthesis[edit | edit source]

Allyltrimethylsilane is used as a reagent in the synthesis of various organic compounds. It is particularly useful in reactions that involve the formation of carbon-carbon bonds.

One of the main uses of allyltrimethylsilane is in the Friedel-Crafts alkylation reaction. In this reaction, the allyl group of the allyltrimethylsilane reacts with an aromatic compound to form a new carbon-carbon bond.

Allyltrimethylsilane is also used in the Mukaiyama aldol addition reaction. In this reaction, the allyl group of the allyltrimethylsilane reacts with a carbonyl compound to form a new carbon-carbon bond.

Safety[edit | edit source]

Like many chemical reagents, allyltrimethylsilane should be handled with care. It is flammable and can cause burns and eye damage. It should be used only in a well-ventilated area and protective clothing, gloves, and eye protection should be worn when handling the compound.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD