Alpha-Chlorocodide
Alpha-Chlorocodide is a synthetic opioid that was developed in the early 20th century. It is a derivative of codeine, but is more potent and has a higher dependency potential.
History[edit | edit source]
Alpha-Chlorocodide was first synthesized in 1914 by the German pharmaceutical company Merck. It was initially used as a cough suppressant and analgesic, but its high potential for abuse led to its classification as a controlled substance in many countries.
Pharmacology[edit | edit source]
Alpha-Chlorocodide is a mu-opioid receptor agonist. It works by binding to these receptors in the brain and spinal cord, which reduces the perception of pain. However, it also produces a euphoric effect, which can lead to dependency and addiction.
Side Effects[edit | edit source]
The side effects of Alpha-Chlorocodide are similar to those of other opioids. They include drowsiness, constipation, nausea, and respiratory depression. In high doses, it can cause severe respiratory depression and death.
Legal Status[edit | edit source]
In the United States, Alpha-Chlorocodide is classified as a Schedule II controlled substance, which means it has a high potential for abuse and is available only by prescription. In the United Kingdom, it is classified as a Class A drug.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD