Alpha-methylfentanyl

Alpha-Methylfentanyl (AMF) is a potent opioid analgesic drug that is an analog of fentanyl. It was first identified in the 1980s during the so-called "designer drug" epidemic. AMF is considered to be several times more potent than morphine.

Chemistry

Alpha-Methylfentanyl is a 3-methylfentanyl analog, differing only by the addition of a methyl group on the alpha carbon. This modification results in a potency level that is 10-20 times greater than that of fentanyl. The chemical formula of Alpha-Methylfentanyl is C22H30N2O.

Pharmacology

Like other opioids, Alpha-Methylfentanyl works by binding to the body's mu-opioid receptor, which is primarily responsible for the effects of opioids. The binding of Alpha-Methylfentanyl to these receptors results in a decrease in the perception of pain, as well as feelings of euphoria and relaxation.

Effects

The effects of Alpha-Methylfentanyl are similar to those of other opioids and include pain relief, sedation, and euphoria. However, due to its high potency, the risk of overdose and death is significantly increased. Symptoms of an overdose can include slow breathing, seizures, and loss of consciousness.

Legal Status

Alpha-Methylfentanyl is a Schedule I controlled substance in the United States, meaning it has a high potential for abuse and no accepted medical use. It is also controlled under similar laws in many other countries.

See Also

• Fentanyl
• Opioid
• Analgesic
• Designer drug

References

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