Amine fluoride

Amine fluoride is an agent which has been researched from past five decades and shown to have a good cariostatic effect with marked reduction in occurrence of plaque induced gingivitis. The active element of amine fluoride is N-octadecyltrimethylendiamine-N, N, N-tris(2-ethonol)-dihydroflouride.

Action of amine fluoride

Being cationic, amine fluoride shows increased sensitivity towards negatively charged bacterial cells. The conventional medium for bacterial growth in the oral cavity starts with pellicle formation, which gets more organised with microorganisms and form a soft biofilm known as dental plaque. Biofilm is more viscous and adhesive, formed on the tooth surface which contains more active bacteria producing acids, causing gingivitis which may progress to periodontitis.

Anti- bacterial and anti- glycolytic action

Researchers have revealed amine fluorides are very much effective against plaque forming bacteria and interfere at the enzymatic acid production. Plaque bacteria like Streptococcus sanguis, Streptococcus mitis, Streptococcus oralis, Streptococcus viscosis and Actinomyces naeslundi are more sensitive towards amide fluorides.

It is also crucial to note that, amine fluorides along with stannous fluorides have shown better results on caries and plaque control, thus reducing the incidence of gingivitis. Amine fluorides have shown their active effect more on the hydrophobic pellicle, than on the tooth surface.

Research has shown that the hydrophobicity on the tooth surfaces varies throughout the day. Tooth will be hydrophophic mainly at night and becomes hydrophilic during active brushing via tooth pastes, stay hydrophilic for a period of time and then becomes hydrophobic.

Amine fluoride Resources
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