Amitraz

From WikiMD's Food, Medicine & Wellness Encyclopedia

Amitraz is a non-systemic acaricide and insecticide. It was discovered and developed by the Boots Company in England. Amitraz has been found to have an insect repellent effect, works as an insecticide and also as a pesticide synergist. Its effectiveness is traced to its ability to inhibit alpha-adrenergic nervous system.

Chemistry[edit | edit source]

Amitraz is part of the formamidine chemical family. It is produced through the reaction of 2,4-dimethylphenylformamidine and methyl isocyanate. The product is an odorless, crystalline solid that is slightly soluble in water. It has a melting point of 86-87 degrees Celsius.

Uses[edit | edit source]

Amitraz is used in agriculture for the control of red spider mite and other mites on apples, pears and other fruit trees, as well as on cotton and other field crops. It is also used on animals, including dogs, to control ticks, mites and lice.

Toxicity[edit | edit source]

Amitraz is a moderately toxic compound in humans, and is classified as a Class III, slightly hazardous pesticide by the World Health Organization. It can cause irritation to the skin and eyes, and can produce symptoms of nervous system depression such as lethargy, confusion, and respiratory depression if ingested or absorbed through the skin in large amounts.

Environmental Impact[edit | edit source]

Amitraz is not very persistent in the environment, with a half-life in soil of 1-32 days. It is moderately toxic to birds and bees, but is highly toxic to fish.

See Also[edit | edit source]

Amitraz Resources
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Contributors: Prab R. Tumpati, MD