Amitriptylinoxide

Amitriptylinoxide is a tricyclic antidepressant (TCA) that was developed in the late 1960s but was never marketed. It is the 10,11-dihydro derivative of amitriptyline.

Pharmacology

Amitriptylinoxide acts as a serotonin-norepinephrine reuptake inhibitor (SNRI) and also blocks the acetylcholine receptor, the latter of which is responsible for its anticholinergic side effects. It is less sedating and has less anticholinergic effect than amitriptyline.

Chemistry

Amitriptylinoxide, also known as 10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-oxide, is a tricyclic compound and is structurally related to other tricyclic antidepressants such as amitriptyline and nortriptyline.

See also

• List of antidepressants
• List of tricyclic antidepressants

References

Amitriptylinoxide Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski