Amyoplasia
Amyoplasia is a rare type of arthrogryposis, a condition characterized by multiple joint contractures and muscle weakness present at birth. The term "amyoplasia" is derived from the Greek words "a" (without), "myo" (muscle), and "plasia" (formation). This condition affects approximately 1 in 10,000 newborns.
Symptoms[edit | edit source]
The most common symptoms of amyoplasia include lack of muscle development and fibrosis (thickening and scarring of connective tissue), particularly in the limbs. Affected individuals typically have flexed and dislocated hips, clubfeet, and flexed fingers. The shoulders may be internally rotated and the elbows may be unable to extend fully. In some cases, the wrists and fingers may also be affected.
Causes[edit | edit source]
The exact cause of amyoplasia is unknown. However, it is believed to be sporadic, meaning it occurs in individuals with no history of the disorder in their family. Some researchers suggest that it may be caused by an early prenatal vascular disruption, which could affect the development of the fetus's limbs and other body parts.
Diagnosis[edit | edit source]
Diagnosis of amyoplasia is typically based on physical examination at birth. The characteristic features of the condition, such as joint contractures and muscle weakness, can often be identified through a physical examination. In some cases, genetic testing may be used to rule out other conditions that can cause similar symptoms.
Treatment[edit | edit source]
Treatment for amyoplasia typically involves physical therapy and, in some cases, surgery. Physical therapy can help improve joint mobility and muscle strength. Surgery may be necessary to correct joint deformities and improve function. The goal of treatment is to improve the individual's ability to perform daily activities and enhance quality of life.
Prognosis[edit | edit source]
The prognosis for individuals with amyoplasia varies. Some individuals may have normal intelligence and lifespan, while others may experience physical disabilities. With appropriate treatment and support, many individuals with amyoplasia can lead productive lives.
See also[edit | edit source]
References[edit | edit source]
Transform your life with W8MD's budget GLP1 injections from $125 and up biweekly
W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.
Why choose W8MD?
- Comprehensive care with FDA-approved weight loss medications including:
- loss injections in NYC both generic and brand names:
- weight loss medications including Phentermine, Qsymia, Contrave, Diethylpropion etc.
- Accept most insurances for visits or discounted self pay cost.
- Generic weight loss injections starting from just $125.00 for the starting dose
- In person weight loss NYC and telemedicine medical weight loss options in New York city available
Book Your Appointment
Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia and visit Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD