Antagonists

From WikiMD's Food, Medicine & Wellness Encyclopedia

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. They are sometimes called blockers; examples include alpha blockers, beta blockers, and calcium channel blockers.

For example, opiod antagonists such as Naltrexone work by blocking the activation of opioid receptors. Instead of controlling withdrawal and cravings, it treats opioid use disorder by preventing any opioid drug from producing rewarding effects such as euphoria.

Antagonists Resources
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Contributors: Prab R. Tumpati, MD