Antibiotic Resistance Lab Network

The Antibiotic Resistance Lab Network (ARLN) is a national initiative in the United States aimed at detecting, responding, and preventing antibiotic resistance. The network is coordinated by the Centers for Disease Control and Prevention (CDC) and involves public health labs across seven regions in the country.

Antibiotic resistance mechanisms

Overview

The ARLN was established in 2016 as part of the CDC's broader efforts to combat antibiotic resistance. The network's primary goal is to rapidly detect and respond to antibiotic resistance threats in healthcare, food, and the community. It also aims to support local and state health departments in their efforts to prevent the spread of resistant infections.

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The Antibiotic Resistance Lab Network logo

Functions

The ARLN performs several key functions:

• Detection: The network uses advanced molecular biology techniques to identify resistant bacteria. This includes whole genome sequencing and other genomic methods.
• Response: When a resistant strain is detected, the ARLN works with healthcare providers, infection control professionals, and public health departments to respond effectively.
• Prevention: The network also supports prevention efforts, such as infection control and antibiotic stewardship programs.

Regional Labs

The ARLN consists of seven regional labs, each serving a specific geographic area. These labs are located in California, Minnesota, New York, Tennessee, Texas, Washington, and Wisconsin. Each lab has a specific focus area, such as carbapenem-resistant Enterobacteriaceae (CRE), Candida auris, or Neisseria gonorrhoeae.

Impact

Since its inception, the ARLN has played a crucial role in detecting and responding to antibiotic resistance threats. It has helped identify numerous outbreaks and has supported the implementation of effective prevention strategies.

See Also

• Antibiotic resistance
• Centers for Disease Control and Prevention
• Molecular biology
• Whole genome sequencing
• Infection control
• Antibiotic stewardship