Arteriovenous anastomosis
Arteriovenous Anastomosis is a specific type of blood vessel connection in the circulatory system that directly connects an artery to a vein, bypassing the capillary bed. This type of connection is primarily found in the human body in the skin and the digestive system, and plays a crucial role in thermoregulation and blood pressure regulation.
Function[edit | edit source]
The primary function of an arteriovenous anastomosis is to regulate body temperature. By bypassing the capillary bed, blood can be rapidly shunted to areas of the body that need to be cooled or warmed. In cold conditions, the arteriovenous anastomoses constrict, reducing blood flow to the skin and thus minimizing heat loss. In warm conditions, they dilate, increasing blood flow to the skin and promoting heat loss.
Arteriovenous anastomoses also play a role in regulating blood pressure. By diverting blood flow away from capillaries, they can help maintain blood pressure in situations where it might otherwise drop, such as during hemorrhage.
Structure[edit | edit source]
Arteriovenous anastomoses are composed of a direct connection between an arteriole and a venule, bypassing the capillary bed. This structure is unique in the circulatory system and is characterized by a lack of endothelial cells that typically line the blood vessels.
Clinical significance[edit | edit source]
Arteriovenous anastomoses are important in a number of clinical contexts. They are often targeted in treatments for hypertension, as their dilation can help reduce blood pressure. Conversely, their constriction can be used to increase blood pressure in cases of hypotension. They are also implicated in certain diseases, such as diabetes, where they can contribute to the development of diabetic foot ulcers.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD