Artesunate/pyronaridine
Artesunate/pyronaridine is a combination medication used for the treatment of malaria. It contains two active ingredients: artesunate, a semi-synthetic derivative of artemisinin, and pyronaridine, a synthetic antimalarial drug. This combination is used to treat uncomplicated Plasmodium falciparum malaria and is also effective against other species of Plasmodium.
Etymology[edit | edit source]
The term "artesunate" is derived from "artemisinin", which is named after the plant Artemisia annua, or sweet wormwood, from which it is extracted. The term "pyronaridine" is a synthetic compound, and its name does not have a known etymology.
Pharmacology[edit | edit source]
Artesunate and pyronaridine work together to kill the malaria parasite. Artesunate is rapidly acting, killing the parasites in the blood within a few hours. Pyronaridine is slower acting but has a longer duration of action, helping to clear any remaining parasites and prevent a relapse.
Side Effects[edit | edit source]
Common side effects of artesunate/pyronaridine include headache, dizziness, and gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Rare but serious side effects can include heart problems and liver damage.
Related Terms[edit | edit source]
- Artemisinin-based combination therapies (ACTs): These are the most effective antimalarial drugs currently available. Artesunate/pyronaridine is one type of ACT.
- Plasmodium: This is the genus of parasites that cause malaria. Artesunate/pyronaridine is effective against several species of Plasmodium.
- Antimalarial medication: This is a type of medication used to prevent or treat malaria. Artesunate/pyronaridine is an antimalarial medication.
See Also[edit | edit source]
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