Astragalus

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Information about Astragalus[edit source]

Astragalus is a traditional Chinese herbal medicine used as a general tonic and treatment for many conditions including diarrhea, upper respiratory infections, heart disease, hepatitis and cancer.

Astragalus monspessulanus
Astragalus monspessulanus

Liver toxicity of Astragalus[edit source]

Astragalus has not been associated with serum enzyme elevations during therapy nor in causing clinically apparent liver injury.

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Mechanism of action of Astragalus[edit source]

Astragalus is an ancient traditional Chinese herbal medicine that is derived from roots of various Astragalus species that are native to China, Korea and North America.

Huang Qi[edit | edit source]

Called “Huang Qi” in Chinese traditional medcine, it is purported to have immunomodulatory, antioxidant, antiviral and cardiotonic activities and is used to treat stress, fatigue, pain, memory loss, viral infections, hypercholesterolemia, cancer, heart failure, and kidney and liver disease. It is also used as a general tonic to increase energy, reduce fatigue and counteract the effects of aging. Its efficacy in these conditions has not been shown in controlled prospective studies, but it has been used in traditional Chinese medicine for centuries and is currently becoming a popular herbal product in Western countries.

Illustration Astragalus glycyphyllos
Illustration Astragalus glycyphyllos

Constituents[edit | edit source]

Astragalus extracts have multiple chemical constituents and the specific active ingredient responsibility for its activity has not been identified. Constituents include triterpene glycosides, saponins (astragalosides), sterols, fatty acids, isoflavonoids and polysaccharides.

Dosage and administration for Astragalus[edit source]

Extracts of astragalus are often supplied as tablets or capsules which are taken once to three times daily. Astragalus is also supplied as liquids and teas.

Side effects of Astragalus[edit source]

Side effects are uncommon and have not been clearly defined. Large doses can cause gastrointestinal upset, diarrhea, nausea and vomiting, probably because of direct irritation to the intestinal mucosa.

Herbal and dietary supplements

Chinese and Other Asian Herbal Medicines

Multi-Ingredient Nutritional Supplements

See also Nutritional supplements

Astragalus Resources
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Contributors: Prab R. Tumpati, MD