Ateline alphaherpesvirus 1
Ateline alphaherpesvirus 1 is a species of virus in the genus Simplexvirus, which is part of the subfamily Alphaherpesvirinae within the family Herpesviridae. This virus is known to infect New World monkeys, particularly those of the family Atelidae, which includes howler monkeys, spider monkeys, and woolly monkeys.
Virology[edit | edit source]
Ateline alphaherpesvirus 1 is a member of the Simplexvirus genus, which is characterized by its ability to establish latent infections in the host's nervous system. Like other alphaherpesviruses, it has a double-stranded DNA genome and is enveloped, meaning it has a lipid membrane surrounding its capsid.
The virus is primarily transmitted through direct contact with infected individuals, and it can cause a range of symptoms from mild to severe, depending on the host species and the individual's immune status. In some cases, it can lead to neurological disease, similar to other herpes simplex viruses.
Pathogenesis[edit | edit source]
The pathogenesis of Ateline alphaherpesvirus 1 involves initial infection of epithelial cells, followed by entry into the nervous system where it can establish latency. During latency, the virus remains dormant within the host's neurons, evading the immune system. Reactivation can occur under certain conditions, leading to recurrent disease.
Host Range[edit | edit source]
Ateline alphaherpesvirus 1 primarily infects New World monkeys of the family Atelidae. These primates are native to Central and South America and are known for their prehensile tails and arboreal lifestyles. The virus has been studied in various species within this family, and it is an important pathogen in captive primate populations.
Diagnosis and Treatment[edit | edit source]
Diagnosis of Ateline alphaherpesvirus 1 infection can be achieved through serological tests, PCR, and virus isolation techniques. Treatment is generally supportive, as there are no specific antiviral drugs approved for use in non-human primates. Management of outbreaks in captive populations involves quarantine and supportive care.
Also see[edit | edit source]
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