Atevirdine
Atevirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that was under development for the treatment of HIV and AIDS. It was developed by Pharmacia & Upjohn but its development was discontinued in the late 1990s due to poor clinical results.
History[edit | edit source]
Atevirdine was first synthesized in the early 1990s as part of a research program by Pharmacia & Upjohn to develop new treatments for HIV and AIDS. The drug was designed to inhibit the reverse transcriptase enzyme, which is crucial for the replication of the HIV virus.
Mechanism of Action[edit | edit source]
Atevirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). NNRTIs work by binding to the reverse transcriptase enzyme, preventing it from converting viral RNA into DNA. This stops the virus from replicating and spreading to new cells.
Clinical Trials[edit | edit source]
Atevirdine underwent several phases of clinical trials in the 1990s. However, the results were disappointing. The drug was found to be less effective than other NNRTIs, and it had a high rate of side effects, including rash and liver toxicity. As a result, Pharmacia & Upjohn decided to discontinue the development of the drug.
Legacy[edit | edit source]
Despite the failure of Atevirdine, the research program that produced it contributed to the development of other NNRTIs that have been successful in treating HIV and AIDS. These include Efavirenz, Nevirapine, and Delavirdine.
See Also[edit | edit source]
This HIV related article is a stub. You can help WikiMD by expanding it.
Transform your life with W8MD's budget GLP1 injections from $125 and up biweekly
W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.
Why choose W8MD?
- Comprehensive care with FDA-approved weight loss medications including:
- loss injections in NYC both generic and brand names:
- weight loss medications including Phentermine, Qsymia, Contrave, Diethylpropion etc.
- Accept most insurances for visits or discounted self pay cost.
- Generic weight loss injections starting from just $125.00 for the starting dose
- In person weight loss NYC and telemedicine medical weight loss options in New York city available
Book Your Appointment
Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia and visit Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD