Azaphen

Azaphen is an antidepressant medication that belongs to the class of tricyclic antidepressants (TCAs). It is primarily used in the treatment of depression and other mood disorders. Azaphen is known for its efficacy in alleviating symptoms of depression, including persistent sadness, loss of interest in activities, and various physical and cognitive symptoms associated with the condition.

Pharmacology

Azaphen works by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine in the brain, which helps to elevate mood and alleviate depressive symptoms. The exact mechanism of action is similar to other tricyclic antidepressants, which block the transporters responsible for the reuptake of these neurotransmitters, thereby increasing their availability in the synaptic cleft.

Indications

Azaphen is indicated for the treatment of:

• Major depressive disorder
• Dysthymia
• Anxiety disorders
• Chronic pain (off-label use)

Side Effects

Common side effects of Azaphen include:

• Dry mouth
• Constipation
• Urinary retention
• Blurred vision
• Drowsiness
• Weight gain

Serious side effects may include:

• Cardiac arrhythmias
• Seizures
• Severe hypotension

Contraindications

Azaphen should not be used in patients with:

• Recent myocardial infarction
• Severe liver impairment
• Hypersensitivity to tricyclic antidepressants

Dosage

The dosage of Azaphen varies depending on the severity of the condition and the patient's response to the medication. It is typically started at a low dose and gradually increased under the supervision of a healthcare provider.

Related Pages

• Antidepressant
• Tricyclic antidepressant
• Serotonin
• Norepinephrine
• Depression (mood)
• Anxiety disorder
• Chronic pain

See Also

• List of antidepressants
• Psychiatry
• Mental health