Azapride
Azapride is a chemical compound that belongs to the class of organic compounds known as benzoylindoles. These are aromatic compounds containing a benzoyl group that is substituted by an indole.
Azapride is used in the field of medicine, specifically in the treatment of various gastrointestinal disorders. It works by acting on the serotonin receptors in the gut, helping to regulate the movement and function of the gastrointestinal tract.
Chemical Structure[edit | edit source]
Azapride has a molecular formula of C16H14N2O2. It is composed of a benzoyl group attached to an indole ring. The indole ring is a bicyclic structure consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring.
Medical Uses[edit | edit source]
Azapride is primarily used in the treatment of gastrointestinal disorders such as irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). It works by acting on the serotonin receptors in the gut, helping to regulate the movement and function of the gastrointestinal tract. This can help to alleviate symptoms such as abdominal pain, bloating, and irregular bowel movements.
Side Effects[edit | edit source]
Like all medications, Azapride can cause side effects. These may include nausea, vomiting, diarrhea, and abdominal pain. In rare cases, it can also cause serious side effects such as allergic reactions and serotonin syndrome, a potentially life-threatening condition caused by excessive levels of serotonin in the brain.
See Also[edit | edit source]
- Benzoylindoles
- Serotonin receptors
- Gastrointestinal disorders
- Irritable bowel syndrome
- Gastroesophageal reflux disease
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Contributors: Prab R. Tumpati, MD