Azinphos methyl

Azinphos methyl is an organophosphate pesticide that was widely used in agriculture. It is also known by its trade names Guthion, Gusathion, and Mezithion.

History

Azinphos methyl was first registered for use in the United States in 1959. It was primarily used to control insects in a variety of crops, including apples, cherries, peaches, pears, and cotton. However, due to its high toxicity and potential for environmental contamination, the Environmental Protection Agency (EPA) phased out its use in 2012.

Chemical Properties

Azinphos methyl is a white crystalline solid with a slight sulfur odor. It is highly soluble in water and most organic solvents. The chemical formula for azinphos methyl is C10H12N3O3PS2.

Toxicity

Azinphos methyl is highly toxic to humans and animals. Exposure can occur through inhalation, ingestion, or skin contact. Symptoms of exposure include nausea, vomiting, diarrhea, abdominal cramps, headache, dizziness, and in severe cases, seizures, respiratory failure, and death.

Environmental Impact

Azinphos methyl is highly toxic to birds, fish, and bees. It can contaminate water sources and has the potential to bioaccumulate in fish. The EPA has classified azinphos methyl as a likely human carcinogen.

Regulation

In 2001, the EPA began a phase-out of azinphos methyl due to its high toxicity and environmental impact. By 2012, all uses of azinphos methyl were cancelled in the United States.

See Also

• Organophosphate poisoning
• Pesticide toxicity to bees
• Environmental impact of pesticides

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