Baltimore classification
Baltimore classification is a system used to categorize viruses based on their manner of mRNA synthesis. The system was developed by Nobel Prize-winning biologist David Baltimore in the early 1970s.
Overview[edit | edit source]
The Baltimore classification system is a key tool in virology, the study of viruses and their functions. It categorizes viruses into seven groups, designated by Roman numerals I through VII. These groups are based on the virus's manner of mRNA synthesis, which is a critical aspect of the virus's lifecycle and replication process.
Classification Groups[edit | edit source]
The seven groups in the Baltimore classification system are:
- Group I: Double-stranded DNA viruses (e.g., Herpesviridae)
- Group II: Single-stranded DNA viruses (e.g., Parvoviridae)
- Group III: Double-stranded RNA viruses (e.g., Reoviridae)
- Group IV: Positive-sense single-stranded RNA viruses (e.g., Picornaviridae)
- Group V: Negative-sense single-stranded RNA viruses (e.g., Orthomyxoviridae)
- Group VI: Positive-sense single-stranded RNA viruses that replicate through a DNA intermediate (e.g., Retroviridae)
- Group VII: Double-stranded DNA viruses that replicate through a single-stranded RNA intermediate (e.g., Hepadnaviridae)
Each group has unique characteristics and includes a variety of virus families.
Importance[edit | edit source]
The Baltimore classification system is important because it provides a framework for understanding the diverse strategies that viruses use to replicate. This knowledge is crucial for the development of antiviral drugs and vaccines.
See Also[edit | edit source]
References[edit | edit source]
- Baltimore, D. (1971). "Expression of animal virus genomes". Bacteriological Reviews, 35(3), 235–241.
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