Bcl
Bcl - human cyclin d1 (bcl1) proto oncogene, located at 11q13, encodes g1/s specific cyclin d1 (ccnd1) protein. Bcl1 gene expression is activated in human b cell lymphomas by translocation, t(11;14)(q13;q32), with immunoglobulin gene regions. Enhanced expression of cyclin d1 protein has also been detected in parathyroid adenomas due to a translocation, t(11;11)(q13;p15), resulting in fusion of bcl1 with the parathyroid hormone enhancer.
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