Besifovir
| Besifovir | |
|---|---|
|
| |
| Chemical nomenclature | |
| IUPAC name | [({1-[(2-Amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methyl]phosphonic acid
|
| Routes | Oral
|
| Identifiers | |
| CAS Number | 441785-25-7 |
| PubChem | 5270766
|
| ChemSpider | 4435660 |
| UNII | 4PLG22CQUU
|
| Chemical data
| |
| Chemical formula | C10H14N5O4 |
| Molecular weight | 299.223022 g/mol |
| SMILES | NC1=NC=C2N=CN(CC3(OCP(O)(O)=O)CC3)C2=N1
|
| InChI | InChI=1S/C10H14N5O4P/c11-9-12-3-7-8(14-9)15(5-13-7)4-10(1-2-10)19-6-20(16,17)18/h3,5H,1-2,4,6H2,(H2,11,12,14)(H2,16,17,18)
|
| InChIKey | KDNSSKPZBDNJDF-UHFFFAOYSA-N
|
Besifovir (INN) is an investigational medication to treat hepatitis B virus (HBV) infection.
It is a novel and potent acyclic nucleotide phosphonate with a similar chemical structure to adefovir and tenofovir.[1]
References[edit]
- ↑ "Hepatitis B virus: new therapeutic perspectives".Liver Int..4 January 2016;36(Supplement S1)
- 85–92.doi:10.1111/liv.13003.PMID:26725903.
-
Besifovir
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