Bimatoprost/timolol

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Bimatoprost/timolol is a combination medication used in the treatment of glaucoma. It contains two active ingredients: bimatoprost and timolol. Bimatoprost is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes. Timolol is a beta blocker that reduces the production of this fluid.

Etymology[edit | edit source]

The name "bimatoprost" is derived from the chemical name of the drug, which is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethylheptenamide. The name "timolol" is derived from the chemical name of the drug, which is (S)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol.

Medical uses[edit | edit source]

Bimatoprost/timolol is used to reduce intraocular pressure in individuals with glaucoma or ocular hypertension. It is typically used when a single medication has not been effective at reducing the pressure.

Side effects[edit | edit source]

Common side effects of bimatoprost/timolol include redness, burning, or itching in the eyes, as well as changes in eyelash length, color, or thickness. More serious side effects can include changes in vision, eye pain, or signs of an allergic reaction.

Related terms[edit | edit source]

  • Glaucoma: A group of eye conditions that damage the optic nerve, often caused by an abnormally high pressure in your eye.
  • Ocular hypertension: A condition characterized by an increase in pressure inside the eye, above the range considered normal.
  • Prostaglandin analogue: A class of drugs designed to mimic the effects of naturally occurring prostaglandins.
  • Beta blocker: A class of drugs that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack after a first heart attack.


Bimatoprost/timolol Resources

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Contributors: Prab R. Tumpati, MD