Biological response modifiers

Biological response modifiers (BRMs) are substances that modify the immune system's response to diseases and conditions. They are used in the treatment of various diseases, including cancer, autoimmune diseases, and infectious diseases. BRMs can be naturally occurring or synthetically produced.

Types of Biological Response Modifiers

There are several types of BRMs, including interferons, interleukins, colony-stimulating factors, monoclonal antibodies, and vaccines.

Interferons

Interferons are proteins produced by the body's cells as a response to viruses, bacteria, parasites, and tumor cells. They interfere with the replication of these pathogens and stimulate the immune system.

Interleukins

Interleukins are a group of cytokines that play an important role in the immune system. They are produced by and act on white blood cells (leukocytes).

Colony-Stimulating Factors

Colony-stimulating factors (CSFs) are substances that stimulate the production of blood cells and promote their ability to function. They are important in the body's response to infection and disease.

Monoclonal Antibodies

Monoclonal antibodies are laboratory-produced molecules that can target specific antigens on the surface of cells. They can be designed to attack specific cells, making them useful in treating certain diseases.

Vaccines

Vaccines are substances that stimulate the immune system to produce an immune response to a specific disease, providing immunity against that disease.

Uses of Biological Response Modifiers

BRMs have a wide range of uses in medicine. They are used in the treatment of various diseases, including cancer, autoimmune diseases, and infectious diseases.

Cancer Treatment

In cancer treatment, BRMs can be used to boost the body's immune system to fight cancer cells. They can also be used to lessen the side effects of other cancer treatments.

Autoimmune Diseases

In the treatment of autoimmune diseases, BRMs can be used to modify the immune system's response, reducing inflammation and other symptoms.

Infectious Diseases

In the treatment of infectious diseases, BRMs can be used to enhance the body's immune response to infection.

See Also

• Immunotherapy
• Immunology
• Pharmacology