Bizarre parosteal osteochondromatous proliferation

Bizarre parosteal osteochondromatous proliferation
Synonyms	Nora's lesion
Pronounce	N/A
Specialty	N/A
Symptoms	Pain, swelling, palpable mass
Complications	Recurrence after surgical removal
Onset	Typically in young adults
Duration	Chronic
Types	N/A
Causes	Unknown
Risks	Unknown
Diagnosis	X-ray, MRI, Histopathology
Differential diagnosis	Osteochondroma, Parosteal osteosarcoma, Myositis ossificans
Prevention	N/A
Treatment	Surgical excision
Medication	N/A
Prognosis	Generally good, but recurrence is possible
Frequency	Rare
Deaths	N/A

Other Names: BPOP; Nora lesion; Nora’s Lesion Bizarre Parosteal Osteochondromatous Proliferation (BPOP), also known as Nora’s lesion, is an uncommon, benign bone tumor that grows on the surface of the bone. In some cases, BPOP does not cause symptoms. However, at other times, it can be painful and lead to bone deformity. It is more commonly located on the hands and feet, but can also affect the long bones or bones of the skull and face. A biopsy of the affected bone is important, as BPOP may resemble malignant bone tumors, especially chondrosarcoma or parosteal osteosarcoma. The cause is still unknown though injuries or bone defects may trigger the condition in some cases. Treatment involves surgery to remove the tumor. There is a 20%-50% chance that the condition may reappear after surgery.

NIH genetic and rare disease info

• NIH info on Bizarre parosteal osteochondromatous proliferation

Bizarre parosteal osteochondromatous proliferation is a rare disease.