Blood thinner

From WikiMD's Food, Medicine & Wellness Encyclopedia

Blood thinners, also known as anticoagulants, are a type of medication that reduces the formation of blood clots. They are used to treat and prevent blood clot disorders such as deep vein thrombosis, pulmonary embolism, and stroke.

Mechanism of action[edit | edit source]

Blood thinners work by interrupting the process of blood clotting. There are two main types of blood thinners: antiplatelet drugs and anticoagulants. Antiplatelet drugs prevent platelets from clumping together to form a clot, while anticoagulants interfere with the proteins needed for blood to clot.

Types of blood thinners[edit | edit source]

There are several types of blood thinners, including:

  • Warfarin (Coumadin): This is a vitamin K antagonist that interferes with the body's use of vitamin K, a nutrient necessary for clotting.
  • Heparin: This is a fast-acting blood thinner used in hospitals to prevent clots from forming or growing.
  • Direct oral anticoagulants (DOACs): These include medications such as dabigatran (Pradaxa), rivaroxaban (Xarelto), and apixaban (Eliquis). They work by directly inhibiting the action of certain clotting factors.

Side effects and risks[edit | edit source]

While blood thinners can be life-saving medications, they also come with risks. The most common side effect is bleeding. This can range from minor bleeding, such as nosebleeds and bleeding gums, to severe bleeding that can be life-threatening. Other side effects can include upset stomach, mild fever, and skin rash.

Monitoring and management[edit | edit source]

Patients on blood thinners often require regular monitoring to ensure the medication is working effectively and safely. This can involve blood tests, such as the International Normalized Ratio (INR) for patients on warfarin, to measure the blood's ability to clot.

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Contributors: Prab R. Tumpati, MD