Boston University CTE Center and Brain Bank

From WikiMD.com Medical Encyclopedia

Research center focused on chronic traumatic encephalopathy


Boston University Medical Campus

The Boston University CTE Center and Brain Bank is a leading research institution dedicated to the study of chronic traumatic encephalopathy (CTE) and other neurodegenerative diseases. Located at the Boston University School of Medicine, the center is renowned for its pioneering work in understanding the long-term effects of repetitive brain trauma.

History[edit | edit source]

The Boston University CTE Center was established to address the growing concern over the impact of repeated head injuries, particularly in contact sports. The center has become a focal point for research into CTE, a condition that has been linked to athletes, military veterans, and others who have experienced repeated brain trauma.

Research Focus[edit | edit source]

The center's primary focus is on CTE, a progressive degenerative disease found in individuals with a history of repetitive brain trauma. The research conducted at the center aims to understand the pathology, diagnosis, and potential treatment of CTE.

Pathology[edit | edit source]

Neurofibrillary tangles in the hippocampus

CTE is characterized by the accumulation of tau protein in the brain, leading to neurofibrillary tangles and other pathological changes. The center's research has been instrumental in identifying these changes and understanding their implications for brain function.

Diagnosis[edit | edit source]

Currently, CTE can only be definitively diagnosed post-mortem. The Boston University CTE Center is at the forefront of developing diagnostic criteria and potential biomarkers that could allow for the diagnosis of CTE in living individuals.

Treatment[edit | edit source]

While there is no cure for CTE, the center is actively involved in research aimed at finding therapeutic interventions that could slow or halt the progression of the disease.

Brain Bank[edit | edit source]

The Boston University Brain Bank is a critical component of the CTE Center. It houses one of the largest collections of brains donated for the study of CTE and other neurodegenerative diseases. The brain bank provides invaluable resources for researchers worldwide.

Notable Cases[edit | edit source]

Aaron Hernandez

The center has studied numerous high-profile cases, including that of Aaron Hernandez, a former NFL player whose post-mortem examination revealed severe CTE. Such cases have brought significant attention to the risks associated with contact sports and have spurred changes in safety protocols.

Public Impact[edit | edit source]

The research conducted at the Boston University CTE Center has had a profound impact on public awareness and policy regarding brain injuries. The center's findings have influenced sports organizations, military protocols, and public health initiatives aimed at reducing the risk of brain trauma.

Related Pages[edit | edit source]

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Contributors: Prab R. Tumpati, MD