Bradley Bernstein

Dr. Bradley Bernstein

Bradley Bernstein is an American biologist and professor known for his contributions to the field of epigenetics and genomics. He is a professor of Cell Biology at Harvard Medical School and a member of the Broad Institute of MIT and Harvard.

Early Life and Education

Bradley Bernstein was born in New York City. He completed his undergraduate studies at Yale University, where he earned a Bachelor of Science degree in Biology. He then pursued a M.D. and a Ph.D. in Biophysics at the University of Washington.

Career

After completing his education, Bernstein joined the faculty at Harvard Medical School and became a member of the Broad Institute. His research focuses on the role of chromatin and epigenetic modifications in gene regulation and cancer.

Research Contributions

Bernstein's work has significantly advanced the understanding of histone modifications and their impact on gene expression. He has been instrumental in mapping the epigenome of various cell types, providing insights into how epigenetic changes can lead to diseases such as cancer.

One of his notable contributions is the discovery of bivalent chromatin domains in embryonic stem cells, which are regions of the genome marked by both activating and repressive histone modifications. This finding has implications for understanding how cells maintain their potential to differentiate into various cell types.

Awards and Honors

Bradley Bernstein has received numerous awards for his contributions to biomedical research, including the Paul Marks Prize for Cancer Research and the NIH Director's Pioneer Award. He is also a member of the American Academy of Arts and Sciences.

Personal Life

Bernstein resides in Boston, Massachusetts, with his family. He is actively involved in mentoring young scientists and contributing to the scientific community through various initiatives.

See Also

• Epigenetics
• Genomics
• Chromatin
• Histone
• Cancer research