Stem cell

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Stem cell differentiation

(stem sel) A stem cell is a cell from which other types of cells develop. For example, blood cells develop from blood-forming stem cells.

Stem cells are unique, unspecialized cells that have the ability to develop into a variety of different cell types in the body. They serve as a form of internal repair system, with the capacity to proliferate and differentiate into more specialized cells, such as blood cells, muscle cells, or nerve cells. [1]

Types of Stem Cells[edit | edit source]

Stem cells can be categorized into several types based on their origin and potential to differentiate.

Embryonic Stem Cells[edit | edit source]

Embryonic stem cells are derived from embryos. These pluripotent cells can differentiate into virtually any type of cell in the body, offering vast therapeutic potential.

Adult Stem Cells[edit | edit source]

Also known as somatic stem cells, adult stem cells are found in various tissues in the body, even after embryonic development. They are more limited in their differentiation potential compared to embryonic stem cells, typically only giving rise to cell types of their tissue of origin.

Induced Pluripotent Stem Cells[edit | edit source]

Induced pluripotent stem cells (iPSCs) are adult cells that have been genetically reprogrammed to an embryonic stem cell-like state. This allows them to differentiate into nearly any type of cell.[1]

Stem Cells and Development[edit | edit source]

In early development, stem cells differentiate into all the specialized cells that form the organism's tissues and organs. For instance, hematopoietic stem cells in the bone marrow can give rise to all the different types of blood cells.

Therapeutic Applications[edit | edit source]

Due to their regenerative abilities and versatility, stem cells have great therapeutic potential. They have been used in therapies for conditions such as leukemia and lymphoma through bone marrow transplants. Researchers are also exploring their use in regenerating damaged tissues or organs.[2]

Research and Ethical Considerations[edit | edit source]

Stem cell research holds promise for understanding basic biological processes and treating a wide range of diseases. However, it also raises significant ethical issues, particularly with respect to embryonic stem cells. The extraction of embryonic stem cells involves the destruction of an embryo, leading to moral and philosophical debates.[3]

See Also[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 "Stem Cell Basics". National Institutes of Health (NIH). Retrieved 2023-05-19.
  2. ↑ "Bone Marrow Transplant". Mayo Clinic. Retrieved 2023-05-19.
  3. ↑ "Ethical Issues in Stem Cell Research". National Center for Biotechnology Information. Retrieved 2023-05-19.

External links[edit | edit source]

Stem cell Resources
Wikipedia





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Contributors: Prab R. Tumpati, MD