Brodmann area 12

Brodmann area 12 is a region of the brain that is part of the prefrontal cortex. It was first identified by the German neurologist Korbinian Brodmann in the early 20th century. Brodmann area 12 is one of the 52 regions of the brain that Brodmann identified based on their cytoarchitectonic characteristics.

Location and Boundaries

Brodmann area 12 is located in the frontal lobe, specifically in the prefrontal cortex. It is bounded by Brodmann area 11 anteriorly, Brodmann area 9 posteriorly, and Brodmann area 10 superiorly.

Function

The exact function of Brodmann area 12 is not fully understood, but it is believed to be involved in cognitive processing, decision making, and emotional regulation. It is also thought to play a role in social cognition, which involves understanding and interpreting the behavior of others.

Clinical Significance

Alterations in Brodmann area 12 have been associated with several neurological and psychiatric conditions, including schizophrenia, bipolar disorder, and major depressive disorder. In addition, damage to this area can result in cognitive impairment and changes in personality.

Research

Research on Brodmann area 12 is ongoing, with scientists using techniques such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) to study its structure and function. These studies are helping to improve our understanding of the role of this area in health and disease.

See Also

• Brodmann area
• Prefrontal cortex
• Frontal lobe
• Cognitive processing
• Social cognition

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