Bromomethyl ethyl ketone

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Bromomethyl ethyl ketone

Bromomethyl ethyl ketone (BMEK) is an organic compound with the formula C₂H₅COCH₂Br. It is a colorless liquid, although commercial samples can appear yellowish due to impurities. BMEK is used primarily in organic synthesis as an intermediate in the production of other chemicals. Its properties as a bromine-containing compound make it a useful reagent in the introduction of bromomethyl groups into organic molecules.

Properties[edit | edit source]

Bromomethyl ethyl ketone has a boiling point of approximately 145-146°C and a density of about 1.4 g/cm³. Being a halogenated ketone, it is reactive and can participate in various chemical reactions, including nucleophilic substitution and condensation reactions. Its bromomethyl group is particularly reactive towards nucleophiles, making it a valuable building block in organic synthesis.

Synthesis[edit | edit source]

The synthesis of bromomethyl ethyl ketone typically involves the halogenation of ethyl methyl ketone (also known as 2-butanone) with bromine. This reaction can be carried out in the presence of a suitable catalyst or under controlled conditions to ensure the selective addition of the bromine atom to the methyl group adjacent to the ketone functionality.

Applications[edit | edit source]

Bromomethyl ethyl ketone is used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its ability to introduce a bromomethyl group into molecules makes it a useful reagent in the modification of chemical structures, potentially altering their physical, chemical, or biological properties. It is also employed in the preparation of polymers, resins, and other materials where the incorporation of bromine atoms can impart desirable characteristics such as flame retardancy.

Safety[edit | edit source]

Handling of bromomethyl ethyl ketone requires caution. It is a toxic and potentially carcinogenic substance. Inhalation or skin contact should be avoided, and appropriate personal protective equipment (PPE) such as gloves and goggles should be worn when working with this chemical. It is also a volatile compound, posing risks of inhalation and flammability. Proper storage and handling procedures must be followed to minimize these risks.

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