Brown-Séquard

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Brown-Séquard syndrome (also known as Brown-Séquard's hemiplegia and Brown-Séquard's paralysis) is a condition that results from damage to one half of the spinal cord, leading to paralysis and loss of proprioception on the same (or ipsilateral) side as the injury or lesion, and loss of pain and temperature sensation on the opposite (or contralateral) side as the lesion. It is named after the physician Charles-Édouard Brown-Séquard, who first described the condition in 1850.

Causes[edit | edit source]

Brown-Séquard syndrome is usually caused by damage to the spinal cord. This can occur due to a variety of reasons, including trauma, tumor, infection, ischemia, or inflammation. In rare cases, it can also be caused by multiple sclerosis or tuberculosis.

Symptoms[edit | edit source]

The symptoms of Brown-Séquard syndrome can vary depending on the exact location and extent of the spinal cord injury. However, common symptoms include:

  • Weakness or paralysis on one side of the body (hemiplegia)
  • Loss of sensation on the same side as the injury
  • Loss of pain and temperature sensation on the opposite side of the injury
  • Difficulty with coordination and balance

Diagnosis[edit | edit source]

Diagnosis of Brown-Séquard syndrome is typically based on the patient's symptoms and medical history. MRI or CT scans may be used to confirm the diagnosis and determine the cause of the syndrome.

Treatment[edit | edit source]

Treatment for Brown-Séquard syndrome primarily involves addressing the underlying cause of the spinal cord injury. This may involve surgery, radiation therapy, or medication, depending on the cause. Physical therapy and occupational therapy may also be beneficial for managing symptoms and improving quality of life.

Prognosis[edit | edit source]

The prognosis for Brown-Séquard syndrome can vary widely depending on the cause and extent of the spinal cord injury. Some individuals may experience significant recovery with treatment, while others may have permanent symptoms.

See also[edit | edit source]

Brown-Séquard Resources
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Contributors: Prab R. Tumpati, MD