Broxyquinoline

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Broxyquinoline is a quinoline derivative with antiseptic and antiprotozoal properties. It is primarily used in the treatment of intestinal amoebiasis and other protozoal infections. Broxyquinoline is known for its effectiveness against a variety of protozoa and some bacteria.

Chemical Properties

Broxyquinoline belongs to the class of quinoline compounds, which are characterized by a benzene ring fused to a pyridine ring. The chemical structure of broxyquinoline includes a hydroxyl group and a bromine atom, which contribute to its antimicrobial activity.

Mechanism of Action

Broxyquinoline works by interfering with the metabolism of protozoal cells. It binds to the DNA of the protozoa, inhibiting their replication and leading to cell death. This mechanism is similar to other quinoline derivatives, which are known to disrupt the nucleic acid synthesis in microorganisms.

Uses

Broxyquinoline is used in the treatment of:

• Intestinal amoebiasis
• Giardiasis
• Trichomoniasis

It is often administered orally and is available in various formulations, including tablets and suspensions.

Side Effects

Common side effects of broxyquinoline include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain

In rare cases, it may cause more severe reactions such as allergic reactions or neurotoxicity.

Precautions

Patients with a history of allergy to quinoline derivatives should avoid using broxyquinoline. It is also important to use this medication under the supervision of a healthcare provider, especially in patients with pre-existing medical conditions.

Related Compounds

• Chloroquine
• Hydroxychloroquine
• Quinine

See Also

• Antiprotozoal
• Amoebiasis
• Giardiasis
• Trichomoniasis

External Links

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