Buphenine

Buphenine is a pharmacological agent that belongs to the class of sympathomimetic drugs. It is primarily used in the treatment of various cardiovascular conditions due to its ability to stimulate the sympathetic nervous system.

Pharmacology[edit | edit source]

Buphenine works by mimicking the effects of norepinephrine, a neurotransmitter that is naturally produced by the body. It binds to adrenergic receptors, specifically the beta-adrenergic receptors, which are found in the heart and blood vessels. This binding action results in the relaxation of smooth muscle in the blood vessels, leading to vasodilation and a decrease in blood pressure.

Medical Uses[edit | edit source]

Buphenine is used in the treatment of several cardiovascular conditions, including hypertension, angina pectoris, and cardiac arrhythmias. It is also used in the management of congestive heart failure to improve cardiac output and reduce the workload of the heart.

Side Effects[edit | edit source]

Like other sympathomimetic drugs, Buphenine can cause a range of side effects. These may include tachycardia, palpitations, nervousness, and insomnia. In rare cases, it can cause severe hypotension or cardiac arrest.

Contraindications[edit | edit source]

Buphenine is contraindicated in patients with hypersensitivity to sympathomimetic drugs, as well as in those with certain cardiovascular conditions such as uncontrolled hypertension, ventricular tachycardia, and pheochromocytoma.