Bupranolol
Overview of the non-selective beta blocker Bupranolol
Bupranolol[edit | edit source]
Bupranolol is a non-selective beta blocker used in the management of hypertension and other cardiovascular conditions. It is known for its ability to block both beta-1 and beta-2 adrenergic receptors, which are involved in the regulation of heart rate and vascular tone.
Pharmacology[edit | edit source]
Bupranolol works by inhibiting the action of epinephrine and norepinephrine on beta receptors, leading to a decrease in heart rate, cardiac output, and blood pressure. This makes it effective in treating conditions such as angina pectoris, arrhythmia, and myocardial infarction.
Mechanism of Action[edit | edit source]
Bupranolol binds to beta-adrenergic receptors, preventing the binding of endogenous catecholamines. This blockade results in decreased sympathetic nervous system activity, which reduces myocardial oxygen demand and improves cardiac efficiency.
Clinical Uses[edit | edit source]
Bupranolol is primarily used in the treatment of:
Side Effects[edit | edit source]
Common side effects of bupranolol include:
Contraindications[edit | edit source]
Bupranolol should not be used in patients with:
- Asthma
- Chronic obstructive pulmonary disease (COPD)
- Severe bradycardia
- Heart block
Related pages[edit | edit source]
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