Butabarbital sodium

Butabarbital Sodium is a barbiturate derivative that is primarily used as a sedative and hypnotic. It is a white, odorless, crystalline powder that is soluble in water and alcohol. Butabarbital Sodium is also known by its trade name, Butisol Sodium®.

Pharmacology

Butabarbital Sodium acts on the central nervous system (CNS) to produce effects ranging from mild sedation to general anesthesia. It works by enhancing the action of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, which results in a decrease in nerve cell activity.

Medical Uses

Butabarbital Sodium is used for the short-term treatment of insomnia. It helps to decrease the time it takes to fall asleep and increases the duration of sleep. However, it is not recommended for long-term use due to the risk of dependence and withdrawal symptoms.

Side Effects

Common side effects of Butabarbital Sodium include drowsiness, dizziness, and headache. Serious side effects may include memory problems, mood changes, and hallucinations. Long-term use can lead to physical and psychological dependence.

Precautions

Butabarbital Sodium should be used with caution in patients with a history of drug abuse or addiction. It should not be used in patients with severe liver disease, respiratory disease, or porphyria. It should also be avoided in pregnant women due to the risk of harm to the fetus.

Interactions

Butabarbital Sodium can interact with other medications, including other CNS depressants, certain antidepressants, and anticoagulants. It can also interact with alcohol, leading to increased sedation and risk of overdose.

See Also

• Barbiturates
• Sedatives
• Hypnotics
• Insomnia
• Dependence
• Withdrawal

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