Butyramide

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Butyramide


Butyramide is an organic compound that belongs to the class of chemical compounds known as amides. It is a derivative of butyric acid, with the chemical formula C4H9NO.

Chemical Structure[edit | edit source]

Butyramide is composed of a butyric acid molecule in which the hydroxyl group (-OH) is replaced by an amide group (-NH2). This results in a molecule with a four-carbon alkyl chain attached to a carbonyl group (C=O) and an amide group.

Properties[edit | edit source]

Butyramide is a white, crystalline solid at room temperature. It has a relatively high melting point for a simple amide, at around 115-118 degrees Celsius. It is slightly soluble in water, and more soluble in organic solvents such as ethanol and ether.

Synthesis[edit | edit source]

Butyramide can be synthesized from butyric acid and ammonia in a process known as amide synthesis. This involves heating the acid and ammonia under pressure, which results in the formation of an ammonium salt. This salt is then heated further to produce butyramide.

Uses[edit | edit source]

While butyramide itself does not have many direct applications, it is used as a precursor in the synthesis of other compounds. For example, it can be used in the production of pharmaceuticals, dyes, and plastics.

Safety[edit | edit source]

Butyramide is not considered to be particularly hazardous, but like all chemicals, it should be handled with care. It can cause irritation to the skin and eyes, and if ingested or inhaled, it can cause nausea and respiratory irritation.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD