C9orf85

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C9orf85 (Chromosome 9 open reading frame 85) is a protein-coding gene located on the short arm of chromosome 9 in humans. The gene is also known by its alias, LOC100506136. The function of the C9orf85 protein is not well understood, and it is currently a subject of ongoing research.

Gene Location and Structure

C9orf85 is situated on the short arm (p arm) of chromosome 9 at position 13.3. The gene spans approximately 10,000 base pairs and consists of multiple exons and introns. The exact structure and number of exons and introns can vary due to alternative splicing.

Protein Function

The precise biological function of the C9orf85 protein remains unclear. However, it is believed to play a role in cellular processes such as cell signaling, cell cycle regulation, and possibly apoptosis. Further research is needed to elucidate its specific functions and interactions with other proteins.

Expression

C9orf85 is expressed in various tissues throughout the body, with higher expression levels observed in certain tissues such as the brain, liver, and kidney. The expression pattern suggests that the protein may have tissue-specific roles.

Clinical Significance

Mutations or alterations in the C9orf85 gene have been investigated for potential links to various diseases, including cancer and neurodegenerative disorders. However, no definitive associations have been established, and more research is required to determine its clinical relevance.

Research Directions

Ongoing studies aim to uncover the molecular mechanisms involving C9orf85 and its potential role in human health and disease. Techniques such as gene knockout, RNA interference, and CRISPR-Cas9 are being employed to study the gene's function in model organisms and cell lines.

See Also

• Chromosome 9
• Protein-coding gene
• Cell signaling
• Apoptosis
• Gene knockout
• CRISPR-Cas9