CCBP2
CCBP2 or Chemokine Binding Protein 2 is a protein that in humans is encoded by the CCBP2 gene. It is also known as ChemR23 or Chemokine Receptor 23.
Function[edit | edit source]
CCBP2 is a receptor for the Chemokine Chemerin. It is expressed in various tissues such as the spleen, liver, and testis. The protein is believed to play a role in the immune system, specifically in the migration of white blood cells to sites of inflammation.
Gene[edit | edit source]
The CCBP2 gene is located on the chromosome 12 (12q13.2-q13.3) and spans approximately 20 kb. The gene contains two exons and one intron.
Clinical significance[edit | edit source]
Mutations in the CCBP2 gene have been associated with Wharton's jelly and umbilical cord abnormalities. Further research is needed to fully understand the implications of these mutations.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
