CCPDMA

CCPDMA

CCPDMA stands for Complete Circumferential Peripheral and Deep Margin Assessment. It is a highly specialized technique used in the surgical treatment of skin cancers, particularly basal cell carcinoma and squamous cell carcinoma. This method is most commonly associated with Mohs micrographic surgery, a procedure that allows for the complete examination of surgical margins to ensure all cancerous cells have been removed.

History

The technique of CCPDMA was developed to improve the accuracy of cancer removal during surgery. Traditional methods often involved removing a tumor with a margin of healthy tissue and then sending the specimen to a pathologist for examination. However, this could result in incomplete excision if cancerous cells were present at the margins. CCPDMA was developed to address this issue by allowing for immediate and thorough examination of the entire surgical margin.

Procedure

In CCPDMA, the surgeon removes the visible tumor along with a thin layer of surrounding tissue. This tissue is then processed and examined under a microscope. The key feature of CCPDMA is that the entire peripheral and deep margins of the excised tissue are examined. This is done by sectioning the tissue in a way that allows for a complete view of the margins, ensuring that no cancerous cells remain.

The process involves:

Excision: The surgeon removes the tumor with a thin layer of surrounding tissue. Mapping: The excised tissue is carefully mapped and oriented to ensure accurate examination. Sectioning: The tissue is frozen and sectioned horizontally, allowing for a complete view of the margins. Microscopic Examination: The sections are stained and examined under a microscope to check for cancerous cells. Re-excision: If cancerous cells are found at the margins, additional tissue is removed and examined until clear margins are achieved.

Advantages

CCPDMA offers several advantages over traditional surgical methods:

• High Cure Rate: By ensuring complete removal of cancerous cells, CCPDMA has a high cure rate, particularly for non-melanoma skin cancers.
• Tissue Conservation: The technique allows for the removal of minimal healthy tissue, preserving as much of the surrounding skin as possible.
• Immediate Results: The examination of margins is done during the surgery, allowing for immediate re-excision if necessary.

Applications

CCPDMA is primarily used in Mohs micrographic surgery, which is considered the gold standard for treating certain types of skin cancer. It is particularly useful for:

• Tumors with ill-defined borders
• Recurrent skin cancers
• Cancers located in cosmetically sensitive areas

Also see

• Mohs surgery
• Basal cell carcinoma
• Squamous cell carcinoma
• Histopathology

Resources

Latest articles - CCPDMA

• Most recent articles
• Ongoing trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on CCPDMA for any updates.

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