CD24

CD24 is a protein that in humans is encoded by the CD24 gene. It is a cell adhesion molecule.

Structure

CD24 is a heavily N-glycosylated GPI-linked cell surface protein. The protein consists of a small peptide backbone, where the mature protein is attached to the GPI anchor. This anchor is attached to the C-terminus of the protein. The protein also has a short N-terminus on the other side of the anchor.

Function

CD24 is a cell adhesion molecule, which is a molecule that aids in the connection of cells. It is involved in the regulation of T cell activation and proliferation. The protein is also involved in apoptosis, the process of programmed cell death. It is expressed in neural tissues and plays a role in the differentiation and function of the nervous system.

Clinical significance

CD24 has been identified as a marker for cancer stem cells. It is expressed in many types of cancer, including breast cancer, ovarian cancer, non-small cell lung cancer, colorectal cancer, and pancreatic cancer. It is also associated with poor prognosis in these cancers.

See also

• Cluster of differentiation
• Cancer stem cell
• Cell adhesion molecule

References

CD24 Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski