CEACAM3
CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3) is a protein that in humans is encoded by the CEACAM3 gene. It is a member of the carcinoembryonic antigen (CEA) gene family.
Function[edit | edit source]
CEACAM3 is an innate immune receptor that is expressed exclusively by human granulocytes. It functions as a pattern recognition receptor for bacteria and triggers an oxidative burst to eliminate the pathogens. The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a cell surface glycoprotein and is highly expressed in neutrophils.
Clinical significance[edit | edit source]
Alterations in the CEACAM3 gene have been associated with susceptibility to infectious disease, particularly bacterial infections. It is also implicated in the progression of certain types of cancer, although further research is needed to fully understand its role in these diseases.
See also[edit | edit source]
References[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
